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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3525fdadb92572239a573b3b568853e3a97461fc57a38cc22bb8cc0c0bb2613f' 
  AND token = 'Eg8O2dPSoRYAgPq68xPrAi4yZaB2aGqEOl/XSTvZ3Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}