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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ada303d7f996593b58082740652cec7c502d5eb7c4e15460262c2bd0acbd2f3' 
  AND token = 'oBAVj6SYj/0ahQasZZAcb0ZYzxVfaxd5Aa8OxVxsmjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}