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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8b3fef0230c7c85a2f84565631a5ed39dc43a0f9aa45c104555002259280615' 
  AND token = 'CT2p/2WjkdCmqTdiPmzfcrVZnJWZw8FgBCc5H7EVZVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}