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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a139d0034b682b319a5f5aa4d3a846261d9b7173ca9ddd7ae0df810a803b721' 
  AND token = '7qpcNDPsNLKqY2qARtFdOsp86fN0kP0CnG/6pd6FyAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}