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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e66727a35320cf78b66b094e24172b552ce939331fad45ed2fceefb18c33769' 
  AND token = 'Kto3/vbRH57WZuN/BfPW+YzEBrM0i73BkoFIY4/Ap68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}