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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6620ace2a97c3187c742fb64355de87605858087b5bf1d7063183916ebd8cbe9' 
  AND token = 'sDFsx+zA5O1qPpQv1M/dZG1kMbN2Xpf71sEphXvJeE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}