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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f15f2ed7fc0425ced4c7c7afd4f65f91524483d4d24ca560b8ddb6107772cad1' 
  AND token = 'hCq++oTFpH0MS7tv+az/8s3XcisHQ5soMkcN7tPHcPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}