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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451f32e8e3d758de1ac81afc4296602df2639ec0a625ba2609b6feb936d78f1b' 
  AND token = 'eiTxNc5WvHFoi8J+DSEJynshwRqiFFBCNz8RpssH5Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}