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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8c49b51bb240f030662599cd4e776fac5810dfe270251b3a98780c8d90fcbfa' 
  AND token = 'm/Z1jOu4El9sC8EqprQadWG23/e+0MOhHqm3R3bf7bY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}