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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa7e2e9fa1f7d441065e7f9b3a018807ef595935e2242b9480e9afbd6ff91648' 
  AND token = 'ldpuoAPqdHxQiLQ4jovA4XBrOVepa7lQYYCNJQ6iVpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}