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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57204fd5feb92f4db7920d497b7ef9eca7eecf41b5e91e5e32c68935a2616b2f' 
  AND token = 'Lp/Mhqyc95L8tcRtC43KjTpDULIdYoyOby0A212/MqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}