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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9750ba57b5c06e1fde675240c51bc18ea1024d22cade3334312bf0ec97fba307' 
  AND token = '+xZwaZvWXeZ3MO1HIcZufnagyr9dPR53BhxF3IkK2gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}