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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4529685c308ea3bdcd74f32ff1c447aafb3743ca2d4fb9352bb9226519fd9c7b' 
  AND token = 'QLAHc4XIJZFsl38P22W3fgb1KVAiAJjbE0NGS9EdQgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}