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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a97262221409f2398e3ee1e6cf2002859faa4d7fdc90d580fdfb3b58e67e949c' 
  AND token = 'cy8S5JVE6SyZKZNODWlZv5unMzUsUiy8Pw4X5COZAPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}