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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23d581b38608ccbff5dbf39c71e857e4f0d6385960dd90759bf46e59089fefc2' 
  AND token = 'zuiLcFD0upMMz99x/mX8ztoqD/aotjSotHLsXPLMQI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}