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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afff7f0bce6c77e815f75b9b98590ffbcf2958672938d978300beee3bf7602d0' 
  AND token = 'HzFMFBFadTpC2K4Dpj2W8Wn+uZsSdixQsqiHrdUzc70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}