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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29f275662cc89ca33dbf9822ad13f03b27ae86bac123b3d2760580b38160572' 
  AND token = 'qzueK1DiA0WPii/l5DPdofyno3UF27GF3pLvkyGs4mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}