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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f342e76eaaacd212b1c081740c7f4f51dde617fbd11b3266254c4f1bff26688d' 
  AND token = 'ELF12Xl4DUxwzzyXN+9bi+EY/7w1QGjU/r9C8Q1rUMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}