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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4083b7dba3c4bf2988d59e8e709dc6b4f7dc7e00a2429bda2dccfbc4eaf1eff' 
  AND token = 'MmtLPnf78tho/eKQKvjilNtVsHwxTv+FWT5XJ7bFMks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}