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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16abc3aeac8b576fed7e85aed1584a5c9fd50be979ba65599c0ef63c3dbf9430' 
  AND token = 'C+RAIsKKfGz1mvco3EkCdCa4Wq4sHXpT9M4RVRhCq6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}