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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5157e52ab134beaa23c3f539af9329159ec2673cc5fd739ee5ddcec3aa659827' 
  AND token = '1G4Ca/vz5v9F4s12rQ/WqbQnWpT4GEdqu2kVtziPYg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}