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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5b09c9f967e012a1ea0b2bc478ac95142542f76e70d64f60c65305ba38c371' 
  AND token = '00wOZZv5oaOeSQjaT/0pHwr0j2pGfhdLlI4XHQlrNcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}