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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5d2a9b78f1feb888afe7ddaa7b60b39fb9a1d64e6065df8744ac19e202fbdf' 
  AND token = 'UPUhr4r6sC2NbIOsaFmkKSmD+6GXDcw/ehWjzZE1ZBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}