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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88997f4460b9c5004884a88953f12e89934615806550e8870752c77035b333ad' 
  AND token = '3A0u30J4vN3IxIHUqbGU/8XLjpEOHIUyEV9t1vhBTxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}