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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d07dd057df06baff2a53930ed5256ea1fa32451c574889b715c0f56aa8ec39a' 
  AND token = 'AvpECgCbc03oaiMxZZ7T4fou8wcUxrN2rbI4PXT7eR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}