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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac958ccb11e80e3ea731dbc4dc460f701a01e1a1fba8dd9e7b15df7cf8e03a0d' 
  AND token = '26ItTl5i7ComIOrHJ9nka2vvDzqvBmWd/6LsMFha1Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}