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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a8ff884f91f5fdfcc62cf08345ac9c4fade3b1e5263a75d3a35028f82be455' 
  AND token = 'y6zfju2T6xwzX4kngQ9bwlHWjfGpmf6cyZ58RuVlmYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}