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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '077d21fa482eb5253a47119713e5c9a1538a51f1c90f7f016a0d0347bfa99701' 
  AND token = 'J8h1RS2pglUOEdfrAwqere/Pc9M3ThRiS7LUWYwNLrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}