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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8d64810327f5fe4600c5085f0b87b825b600a9f4e03b6f3dcf27e52284f8e8' 
  AND token = 'uQXKzn83pmHH9/OVjEV5Ddswej4sBIwVr+lEL7UXipU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}