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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c93e727ed3b72c4bb31ceb3698aec2e311e0ac55b340a74f0701b4093519d4b5' 
  AND token = 'cxN5WttDE1SNKGwDUbxd6JiC/2T2AIBuJxtd2oBql84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}