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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1333af52d2c4b3e74071104b03a654d68b45bcb7789875955b61551539511df4' 
  AND token = '8bnOLzeZa4o4vUOreLLGUYN5IAfX3fLWLZiZVuusSL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}