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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d0cff36c181a8ae7a50f2357089918b1d107a89e60a9ae9b8809a602f6ff81' 
  AND token = '5MRGZL+JNkGGXZ/3aDDG0Qxtvb6/6Q1Kn80N0v7xWOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}