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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f89b6cfecaf033934578f438aa528bd14b6c75d283f7f7905b4e8cc90e4dfab' 
  AND token = 'HDsoQr9VHLJe8LaQX5U2mwAV7M9+sAhSTa40NY/KxW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}