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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a86f195a9976594e8211716b1df8244819e2b973449f98bc78dd511a6d01690' 
  AND token = '4LKMvrXuiZlV8ma7yDiTMmISJsyRrRbSTQ1cLVYt+HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}