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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19e71cd9ba7c6d8330247ce2395f138818f6683c84710613f3115dfcdf7f45b6' 
  AND token = 'VRsyOlm8uGGr7msX/b44vIpzTOFfKbaEdQBVc6qYOkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}