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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f517b4826e0033cd01d45544e2e41a6bf3a3e5f86542c4ad424f2b8e42eeab7b' 
  AND token = 'ZDPIARltY0xsPdukOGHusm9n9hiZIAc1CXM5lo2cXsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}