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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14246717ed860431d694bc70efceb43bc10a0e7573908e3d7b07d9668dbb3d41' 
  AND token = 'AQrHXHVTDiaS+WWXvN5/mb2eu8y5lHn0SxUOJVXqo+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}