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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387be12c8bd2bca8d71687879fc4d135c238095fe39afaed2ef962c2a9e526b6' 
  AND token = 'Aq/LHt7T78r5eKpzyHYxdR4b4tOoYB7ekp3Cm7F6Yic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}