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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '009a18670979e3d5a6dc56199ff3609f0ed5633f3ea0081e2ab1d31fadcb9edb' 
  AND token = 'TUdp+rv954g6uhIAJ9Xad1nyBTTy3n1xTn0j2PEZoXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}