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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a6dd70d6e97aba17d8dcd2ebe7b3283f221bfaba8ff1890a68d4b11158d4162' 
  AND token = 'k1jFL8EMi4Hr8tbzp/5fwB4Mq4r3jLDL05GsaCr6/3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}