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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '040d25010b8cecc284062ce387b8f57d9ee9d913e01c3f04ae09d19069eb98ea' 
  AND token = '0xWkCIkQVL+72l7i1iopdoWNWDhQcSru3Bb8UNNS2vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}