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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee1dd943f1b0700cdf2bed78c070356b198540e20c27f3d537dcc60278112a98' 
  AND token = '8GbvCe1cELSnO1XxB1MfTK3NsT9vBuSlTO0ICQALLZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}