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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3ff53a29343982030fad24eec03bd4d2b37e98d1ff064fd30e1ee0b0788011' 
  AND token = 'Z2h2Eg5m+Ss1TBWHlQ76/WTE/by+Dpt3llIHLFwIllQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}