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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4666b5df0f79b5d4e2503769e9fa9047945e19d3b021341a7beb71eb146429f5' 
  AND token = 'uVz0oO2+lS63HHGODUGh73eVG6FRRwB6iTpykh009SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}