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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77f0f0189e6ab709dd04777950787ce6de5e399e49110004469cb95d6c37c1ae' 
  AND token = '0T16yXeg+WNV//jTG47UkMiC+3Eqyuw7PNinUa0D2ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}