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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea28d52a2e572e0160c126b33b5dc0d4289a47ed0dc5a4bbd8db51ba83e9429a' 
  AND token = '5kBiuzOe125EuMbfyxDzGCIP6VlgCvaXAmCeCtHLcso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}