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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5c35b4c84e43a897bdb5b3961f1381e4114f81d75fdeeb7c11e55f0d8f9160' 
  AND token = '00XZQseo3p3JWQpvPzfMiLjmCEahQU6ixJlerlXUQZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}