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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e72a759ab4c25245fa884106710f4465722b9594e0b3aec80e8ede7b19d4ec60' 
  AND token = 'u8wiO4ohwcRqfiSm8BaZi9XHzD5e6EOp+7JNuGCPXyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}