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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c197cb4ec2c9ccf04905d425b9c104fce09d637e2b88344fb1c609ed5e0151' 
  AND token = 'UKVCTcko6g6YfatObnAWLy4SLXXzS6UHyHGEefrEEWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}