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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e196fb027424b42aafbbdd4502dbe2c30c1c57af15f6fe18ab78183a251503c' 
  AND token = 'LrCpu4j9x8m21pDripdNG7HVqI5EpfmE45payKT4tlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}